Intestinal Transplantation: Current Status

Jonathan Paul Fryer*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations

Abstract

Intestine transplant is indicated for patients with intestinal failure who are unable to be weaned from parenteral nutrition (PN). Long-term PN, although life sustaining in many patients, can be associated with life-threatening complications including PN-associated liver disease (PNALD). Most patients are not considered for intestine transplant until they have developed severe PNALD and also need a liver transplant. Overall outcomes with intestinal transplantation are steadily improving, and current 1-year patient survivals for intestine-only transplants are now similar to those for liver transplant. Intestinal transplantation should be considered earlier in intestinal failure patients who are at high risk for developing PNALD and other life-threatening complications.

Original languageEnglish (US)
Pages (from-to)145-159
Number of pages15
JournalGastroenterology Clinics of North America
Volume36
Issue number1
DOIs
StatePublished - Mar 1 2007

ASJC Scopus subject areas

  • Gastroenterology

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