A study on the cardiac pacemaker current if in inside-out macro-patches of sino-atrial (SA) node cells has recently demonstrated that if channels are directly activated by intracellular cAMP . Using the same preparation, here we investigate the possibility that internal Ca2+ ions play a role in the modulation of if channels. Our results indicate that Ca2+ ions do not have a direct activating effect on if.
|Original language||English (US)|
|Number of pages||3|
|Journal||Pflügers Archiv European Journal of Physiology|
|State||Published - Dec 1 1991|
ASJC Scopus subject areas
- Clinical Biochemistry
- Physiology (medical)