Intracellular recordings from supporting cells in the guinea-pig cochlea: AC potentials

Elizabeth C. Oesterle, Peter Dallos

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Supporting cells and hair cells from the low-frequency region of the guinea-pig cochlea were studied in vivo using intracellular recording and horseradish peroxidase marking techniques. Response characteristics of the support cells to tone bursts at various sound levels, frequencies, and durations were compared to hair-cell responses and potentials recorded in the organ of Corti fluid spaces. Findings suggest that the fundamental component of the support-cell response accrues from hair-cell-generated currents. This component of the support-cell response probably results from the flow of receptor currents across support-cell membranes through nonspecialized membrane patches, or across nonspecialized membranes and through gap junctions that couple adjacent support cells. Findings suggest a lack of electrotonic coupling between hair cells and neighboring support cells.

Original languageEnglish (US)
Pages (from-to)1013-1032
Number of pages20
Journaljournal of the Acoustical Society of America
Volume86
Issue number3
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Acoustics and Ultrasonics

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