TY - JOUR
T1 - Intracerebral Hemorrhage. New Challenges and Steps Forward.
AU - Provencio, Jose Javier
AU - Ferreira Da Silva, Ivan Rocha
AU - Manno, Edward Michael
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013/7
Y1 - 2013/7
N2 - Intracerebral hemorrhage (ICH) is a significant cause of morbidity and mortality. With the aging population, increased use of anticoagulants, and changing racial and ethnic landscape of the United States, the incidence of ICH will increase over the next decade. Improvements in preventative strategies to treat hypertension and atrial fibrillation are necessary to change the trajectory of this increase. Advances in the understanding of ICH at the vascular and molecular level may pave the way to new treatment options. This article discusses the epidemiology, pathophysiology, and current treatment options for patients with ICH. Differences in outcome and treatment between patients taking and not taking anticoagulant therapies are considered.
AB - Intracerebral hemorrhage (ICH) is a significant cause of morbidity and mortality. With the aging population, increased use of anticoagulants, and changing racial and ethnic landscape of the United States, the incidence of ICH will increase over the next decade. Improvements in preventative strategies to treat hypertension and atrial fibrillation are necessary to change the trajectory of this increase. Advances in the understanding of ICH at the vascular and molecular level may pave the way to new treatment options. This article discusses the epidemiology, pathophysiology, and current treatment options for patients with ICH. Differences in outcome and treatment between patients taking and not taking anticoagulant therapies are considered.
KW - Acute brain injury
KW - Anticoagulation
KW - Intracerebral hemorrhage
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U2 - 10.1016/j.nec.2013.03.002
DO - 10.1016/j.nec.2013.03.002
M3 - Review article
C2 - 23809030
AN - SCOPUS:84879785523
SN - 1042-3680
VL - 24
SP - 349
EP - 359
JO - Neurosurgery clinics of North America
JF - Neurosurgery clinics of North America
IS - 3
ER -