The effect of phospholipase A 2 (PLA 2 )-filled bioreactor on the cholesterol level of hypercholesterolemic New Zealand white rabbits was characterized. Bioreactors were constructed by immobilizing the enzyme to beads with amino residues and packing the beads with the enzyme into the hollow fiber. Enzymatic activity was monitored by titrating the reaction between PLA 2 and the substrate L-alpha-phosphatideylcholine dipalmitoyl with sodium hydroxide.
|Original language||English (US)|
|Journal||Artificial Cells, Blood Substitutes, and Immobilization Biotechnology|
|State||Published - Nov 1 1994|
|Event||Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA|
Duration: Jul 24 1994 → Jul 27 1994
ASJC Scopus subject areas
- Biomedical Engineering