Intracranial complications of pediatric hematologic disorders: Computed tomographic assessment

Richard M. Gore, Peter E. Weinberg*, Eugene Anandappa, Arnold Shkolnik, Harvey White

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Computed tomography (CT) findings in the intracranial complications of leukemia, hemophilia, and sickle cell anemia were reviewed in 19 children with these hematologic disorders. CT demonstrated intracranial hemorrhage, infarction, intracerebral mass, and post-therapeutic atrophy and leukoencephalopathy in leukemic children. Intracerebral, subarachnoid, subdural, and epidural hemorrhage was documented in patients with hemophilia. Bland and hemorrhagic infarctions were identified in children with sickle cell anemia. CT proved valuable in documenting the presence and extent of these abnormalities, titrating factor replacement in hemophiliac patients, and monitoring therapeutic toxicity in leukemic patients.

Original languageEnglish (US)
Pages (from-to)175-180
Number of pages6
JournalInvestigative radiology
Volume16
Issue number3
DOIs
StatePublished - Jan 1 1981

Keywords

  • Cranial computed tomography
  • Hemophilia
  • Leukemia
  • Leukoencephalopathy
  • Radionecrosis
  • Sickle cell anemia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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