Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis

Suneel D. Kamath; Priya U. Kumthekar; Tim J. Kruser; Nisha A. Mohindra

doi:10.1634/theoncologist.2018-0022

Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis

Suneel D. Kamath^*, Priya U. Kumthekar, Tim J. Kruser, Nisha A. Mohindra

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Central nervous system metastasis in non-small cell lung cancer remains a therapeutic challenge and confers a poor prognosis. Here we describe a patient with lung adenocarcinoma, parenchymal brain metastases, and leptomeningeal carcinomatosis who demonstrated a sustained response to programmed death 1 inhibition combined with stereotactic radiosurgery.

Original language	English (US)
Pages (from-to)	e159-e161
Journal	Oncologist
Volume	23
Issue number	12
DOIs	https://doi.org/10.1634/theoncologist.2018-0022
State	Published - Dec 2018

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1634/theoncologist.2018-0022

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title = "Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis",

abstract = "Central nervous system metastasis in non-small cell lung cancer remains a therapeutic challenge and confers a poor prognosis. Here we describe a patient with lung adenocarcinoma, parenchymal brain metastases, and leptomeningeal carcinomatosis who demonstrated a sustained response to programmed death 1 inhibition combined with stereotactic radiosurgery.",

author = "Kamath, {Suneel D.} and Kumthekar, {Priya U.} and Kruser, {Tim J.} and Mohindra, {Nisha A.}",

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AU - Kumthekar, Priya U.

AU - Kruser, Tim J.

AU - Mohindra, Nisha A.

PY - 2018/12

Y1 - 2018/12

N2 - Central nervous system metastasis in non-small cell lung cancer remains a therapeutic challenge and confers a poor prognosis. Here we describe a patient with lung adenocarcinoma, parenchymal brain metastases, and leptomeningeal carcinomatosis who demonstrated a sustained response to programmed death 1 inhibition combined with stereotactic radiosurgery.

AB - Central nervous system metastasis in non-small cell lung cancer remains a therapeutic challenge and confers a poor prognosis. Here we describe a patient with lung adenocarcinoma, parenchymal brain metastases, and leptomeningeal carcinomatosis who demonstrated a sustained response to programmed death 1 inhibition combined with stereotactic radiosurgery.

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Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis

Abstract

ASJC Scopus subject areas

UN SDGs

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