Intrahepatic portal-hepatic venous anastomosis: A portal-systemic shunt with neurological repercussions

Jeffrey Crespin, Albert Nemcek, Gina Rehkemper, Andres T. Blei*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Intrahepatic shunts are rarely diagnosed as a cause of neurocognitive abnormality. A complaint of fatigue led to the diagnosis of right portal vein-hepatic vein aneurysmal communication in a 23-yr-old, otherwise healthy woman. Neuropsychological testing, imaging, and MR spectroscopy revealed changes similar to those described in patients with cirrhosis and subclinical hepatic encephalopathy. T1-weighted MRI showed a hyperintense globus pallidus, a feature seen in subjects with and without portal-encephalopathy. Portal-systemic shunting in the absence of parenchymal liver disease reproduces neurological features described in cirrhosis. (C) 2000 Am. Coll. of Gastroenterology.

Original languageEnglish (US)
Pages (from-to)1568-1571
Number of pages4
JournalAmerican Journal of Gastroenterology
Issue number6
StatePublished - Jun 2000

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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