Intraocular reticulum cell sarcoma: clinico pathologic study of four cases and review of the literature

Four patients with primary intraocular reticulum cell sarcoma were presented. All of the patients were followed up for periods of up to 10 yr. All had decreased visual acuity and a uveitis that was refractory to standard forms of therapy. In one case, the correct diagnosis was made clinically. At autopsy, 2 of the patients had systemic reticulum cell sarcoma, a third had intracranial reticulum cell sarcoma, and in a fourth case the disease process was confined to the eye. The literature is reviewed and the clinico pathologic features of the total of 14 cases are analyzed. It is emphasized that a recalcitrant uveitis was present in almost all of the cases reported. Differential diagnosis and methods of diagnosis are discussed.