Intraoperative pediatric blood transfusion therapy: A review of common issues. Part I: Hematologic and physiologic differences from adults; metabolic and infectious risks

Sandra L. Barcelona*, Alexis A. Thompson, Charles J. Coté

*Corresponding author for this work

Research output: Contribution to journalReview article

34 Scopus citations


Pediatric intraoperative transfusion therapy, particularly the approach to massive blood transfusion (blood loss ≥one blood volume) can be quite complex because of the unique relationship between the patient's blood volume and the volume of the individual blood product transfused. This paper is divided into two parts: part 1 presents an overview of the physiologic and hematologic differences between children and adults as well as an overview of the metabolic consequences of blood transfusions, risks of disease transmission, and blood compatibility issues.

Original languageEnglish (US)
Pages (from-to)716-726
Number of pages11
JournalPaediatric anaesthesia
Issue number9
StatePublished - Sep 1 2005



  • Disease transmission
  • Hyperkalemia
  • Hypocalcemia
  • Hypomagnesemia
  • Hypothermia
  • Massive blood transfusion
  • Transfusion therapy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anesthesiology and Pain Medicine

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