Intraplacental smooth muscle tumor: A case report

Linda M. Ernst, Pei Hui, Vinita Parkash*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


We present the second reported case of a smooth muscle neoplasm involving the placental parenchyma. On gross examination, the tumor easily separated from the uterus and had a whorled cut surface with finger-like extensions into the villous parenchyma, very similar to the previously described case. The differential diagnosis included a primary smooth muscle tumor of the placenta (placental leiomyoma), a primary uterine neoplasm incorporated into the placenta, and a metastatic sarcoma. In this case, the infant was male, and the polymerase chain reaction technique demonstrated the presence of Y chromosome gene in the placental parenchyma and its absence in the placental neoplasm. Thus, this neoplasm, despite its gross appearance of a primary placental tumor, actually represented an incorporated benign uterine leiomyoma.

Original languageEnglish (US)
Pages (from-to)284-288
Number of pages5
JournalInternational Journal of Gynecological Pathology
Issue number3
StatePublished - Jan 1 2001


  • Intraplacental
  • Leiomyoma
  • Placenta
  • Smooth muscle tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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