Intravital imaging of host–parasite interactions in skin and adipose tissues

Mariana De Niz*, Gavin R. Meehan, Nicolas M.B. Brancucci, Matthias Marti, Brice Rotureau, Luisa M. Figueiredo, Friedrich Frischknecht

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

Intravital microscopy allows the visualisation of how pathogens interact with host cells and tissues in living animals in real time. This method has enabled key advances in our understanding of host–parasite interactions under physiological conditions. A combination of genetics, microscopy techniques, and image analysis have recently facilitated the understanding of biological phenomena in living animals at cellular and subcellular resolution. In this review, we summarise findings achieved by intravital microscopy of the skin and adipose tissues upon infection with various parasites, and we present a view into possible future applications of this method.

Original languageEnglish (US)
Article numbere13023
JournalCellular Microbiology
Volume21
Issue number5
DOIs
StatePublished - May 2019

ASJC Scopus subject areas

  • Virology
  • Microbiology
  • Immunology

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