Invasive filamentous growth of Candida albicans is promoted by Czf1p-dependent relief of Efg1p-mediated repression

Angela D. Giusani, Marcelo Vinces, Carol A. Kumamoto*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

80 Scopus citations

Abstract

Filamentation of Candida albicans occurs in response to many emironmental cues. During growth within matrix, Efg1p represses filamentation and Czf1p relieves this repression. We propose that Czf1p interacts with Efg1p, altering its function. The complex regulation of filamentation may reflect the versatility of C. albicans as a pathogen.

Original languageEnglish (US)
Pages (from-to)1749-1753
Number of pages5
JournalGenetics
Volume160
Issue number4
StatePublished - 2002
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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