Invasive filamentous growth of Candida albicans is promoted by Czf1p-dependent relief of Efg1p-mediated repression

Angela D. Giusani; Marcelo Vinces; Carol A. Kumamoto

Invasive filamentous growth of Candida albicans is promoted by Czf1p-dependent relief of Efg1p-mediated repression

Angela D. Giusani, Marcelo Vinces, Carol A. Kumamoto^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

Filamentation of Candida albicans occurs in response to many emironmental cues. During growth within matrix, Efg1p represses filamentation and Czf1p relieves this repression. We propose that Czf1p interacts with Efg1p, altering its function. The complex regulation of filamentation may reflect the versatility of C. albicans as a pathogen.

Original language	English (US)
Pages (from-to)	1749-1753
Number of pages	5
Journal	Genetics
Volume	160
Issue number	4
State	Published - 2002
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Invasive filamentous growth of Candida albicans is promoted by Czf1p-dependent relief of Efg1p-mediated repression",

abstract = "Filamentation of Candida albicans occurs in response to many emironmental cues. During growth within matrix, Efg1p represses filamentation and Czf1p relieves this repression. We propose that Czf1p interacts with Efg1p, altering its function. The complex regulation of filamentation may reflect the versatility of C. albicans as a pathogen.",

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T1 - Invasive filamentous growth of Candida albicans is promoted by Czf1p-dependent relief of Efg1p-mediated repression

AU - Giusani, Angela D.

AU - Vinces, Marcelo

AU - Kumamoto, Carol A.

PY - 2002

Y1 - 2002

N2 - Filamentation of Candida albicans occurs in response to many emironmental cues. During growth within matrix, Efg1p represses filamentation and Czf1p relieves this repression. We propose that Czf1p interacts with Efg1p, altering its function. The complex regulation of filamentation may reflect the versatility of C. albicans as a pathogen.

AB - Filamentation of Candida albicans occurs in response to many emironmental cues. During growth within matrix, Efg1p represses filamentation and Czf1p relieves this repression. We propose that Czf1p interacts with Efg1p, altering its function. The complex regulation of filamentation may reflect the versatility of C. albicans as a pathogen.

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AN - SCOPUS:0036240684

SN - 0016-6731

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JO - Genetics

JF - Genetics

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ER -

Invasive filamentous growth of Candida albicans is promoted by Czf1p-dependent relief of Efg1p-mediated repression

Abstract

ASJC Scopus subject areas

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