Is there a role for antibiotics in the treatment of chronic rhinosinusitis?

Stephanie Shintani Smith*, Raymond Kim, Richard Douglas

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Rhinosinusitis is one of the most common reasons for adult outpatient antibiotic prescriptions, though there is little clinical evidence to support this practice, especially for chronic rhinosinusitis. Despite considerable research, the etiology of chronic rhinosinusitis, including the pathogenic role of microbes, remains poorly understood. Rigorous studies of the efficacy of antibiotic treatment of chronic sinusitis are surprisingly few in number and the results are somewhat conflicting. This review article will review the rationales for and against the treatment of chronic rhinosinusitis with antibiotics, based on current evidence and understanding of pathophysiology, and will also summarize the current guidelines.

Original languageEnglish (US)
Pages (from-to)1504-1512
Number of pages9
JournalJournal of Allergy and Clinical Immunology
Issue number5
StatePublished - May 2022


  • Chronic rhinosinusitis
  • antibiotics
  • review article

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


Dive into the research topics of 'Is there a role for antibiotics in the treatment of chronic rhinosinusitis?'. Together they form a unique fingerprint.

Cite this