Isolated gallbladder intramucosal metastatic melanoma with features mimicking lymphoepithelial carcinoma

Amy A. Lo, Joseph Peevey, Edward C. Lo, Joan Guitart, Sambasiva Rao Musunuri, Guang-Yu Yang*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Malignant melanoma has a variety of morphologic patterns and can metastasize and mimic any type of neoplastic process creating significant diagnostic difficulty. When metastasis to the gastrointestinal system is identified, it is most commonly associated with widely metastatic disease. We report a rare case of isolated gallbladder intramucosal metastatic melanoma with features mimicking lymphoepithelial carcinoma in an adult patient who presented with cholecystitis. Additionally, we report the imaging and morphologic features and discuss the importance of these findings along with a clear clinical history and immunohistochemical profile to make a definitive diagnosis.

Original languageEnglish (US)
Pages (from-to)409-413
Number of pages5
JournalInternational Journal of Surgical Pathology
Volume23
Issue number5
DOIs
StatePublished - May 1 2015

Keywords

  • Gallbladder
  • Intramucosal metastasis
  • Metastatic melanoma

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

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