A clone, containing a 24-dinucleotide (CA)-repeat sequence, was isolated from chromosome 8q24.1 band-specific pUC19 library. It was localized to target chromosome using human-rodent hybrid cell panel. Eleven alleles were estimated from 56 unrelated individuals and the heterozygosity reaches 0.835. Linkage analysis of 11 Chinese pedigrees showed significant evidence for linkage of this new marker to three dinucleotide repeat markers at 8q23-24.1 region, with the most likely position of the marker between D8S85 and D8S199.
|Original language||English (US)|
|Number of pages||4|
|Journal||Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University|
|State||Published - 1997|
ASJC Scopus subject areas