Isolation of band-specific (CA)n microsatellites from human chromosome 8q24.1

Lei Xu*, Jiahui Xia, Qian Pan, Tao Cai, Hanxiang Deng

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Fourty eight recombinant plasmids containing CA repeats were isolated from human chromosome 8q24.1 band-specific pUC19 library. Among them, inserted DNA fragments from 12 plasmids were sequenced, and one new highly polymorphic (CA)n microsatellite was obtained (coding: D8S7F). It contained 11 alleles. The estimated heterozygosity reached 0.84 and 0.83 among Chinese Han Nationality people and American Anglo-Saxons respectively. It was assigned to chromosome 8 by using a human-rodent hybrid cell panel.

Original languageEnglish (US)
Pages (from-to)4-6
Number of pages3
JournalActa Genetica Sinica
Volume24
Issue number1
StatePublished - Dec 1 1997

Keywords

  • (CA)
  • Chromosome band-specific
  • Microsatellite DNA
  • pUC19 library

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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