Isometric force control in schizophrenic patients with tardive dyskinesia

P. Bart Vrtunski*, Larry D. Alphs, Herbert Y. Meltzer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Force control (FC) function, considered to be a constituent component of motor output, was investigated in psychiatric patients with dyskinetic impairments. Twenty-one patients with mild-to-moderate tardive dyskinesia were compared to 25 nondyskinetic patients on an FC test for both hands and oromandibular region. Results indicate that FC impairment is readily observed in dyskinetic subjects. The FC steadiness (i.e., the ability to maintain a sustained force output) in dyskinetic and control subjects was found to be inversely proportional to the amount of force generated. This method provides an objective, simple, and precise quantification of motor impairment along a force-defined continuum. It may be useful in studying tardive dyskinesia and the effects of neuroleptic medication on motor output control.

Original languageEnglish (US)
Pages (from-to)57-72
Number of pages16
JournalPsychiatry Research
Issue number1
StatePublished - Apr 1991


  • Schizophrenia
  • sustained force control
  • tardive dyskinesia
  • voluntary movement

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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