Abstract
Transferable skills: Enantiomerically pure isothioureas promote the 0-to C-carboxyl group transfer of oxazolyl carbonates with excellent levels of enantiocontrol (see scheme). The origin of the enantioselectivity of this process was probed mechanistically and rationalized computationally.
Original language | English (US) |
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Pages (from-to) | 8914-8918 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 47 |
DOIs | |
State | Published - Nov 9 2009 |
Keywords
- Asymmetric catalysis
- Carboxy group transfer
- Heterocycles
- Isothloureas, organocatalysis
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)