This chapter discusses the factors associated with juvenile osteoporosis. Osteoporosis is a disease process of bone fragility associated with reduced bone mass in children. Juvenile Osteoporosis (JOP) may occur in an idiopathic manner, termed as "idiopathic JOP" (IJOP), or may be secondary to one of the numerous diseases. Bone density measurements should be interpreted with caution in growing children, because of the variability in machines for measuring bone density and other factors. The clinical symptoms and signs of JOP are provided- such as bone pain, mild myopathy, and associated scoliosis. The radiographic, biochemical, and histomorphometric findings of bone in IJOP are discussed in this chapter. The basic causes of Osteoporosis in children and adolescents are: (1) IJOP, (2) developmental disorders of bone and cartilage, (3) metabolic bone diseases primary, and (4) metabolic bone diseases secondary. The proposed treatments for IJOP are biophosphonate therapy, orthopedic procedures, and normal dietary intake of calcium.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)