Kaposi's sarcoma in women with AIDS

Timothy P. Cooley*, Lisa R. Hirschhorn, J. Connor O'Keane

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Objective: To describe the presentation and incidence of Kaposi's sarcoma (KS) in a cohort of women infected with HIV and to compare their clinical characteristics with men at the same institution. Design: Retrospective chart and database review. Setting: Adult clinical AIDS program outpatient clinics at a municipal teaching hospital. Results: One hundred and seven people with KS were found of whom twelve (11.2%) were women. The prevalence of KS in women was 3.6% compared with 9.9% among men (P < 0.001). Women born outside the United States were at increased risk of developing KS (P < 0.05). At initial KS presentation, no difference in HIV stage or CD4 count was found between men and women. Women presented with more advanced KS than men, with increased incidence of non-cutaneous disease (P < 0.001), lymphedema (P < 0.0001), lymph-node disease (P < 0.0001) and visceral disease (P = 0.03). Women had decreased survival after KS diagnosis compared to men, although the difference was not significant (P = 0.41). Conclusions: KS is not a rare diagnosis in HIV-infected women followed at our institution. Although the increased risk of KS in men is most likely to be related to differences in exposure, the sex-related differences in presentation and course may be due in part to delay in diagnosis. KS should be considered in the spectrum of HIV-related complications in women as well as in men.

Original languageEnglish (US)
Pages (from-to)1221-1225
Number of pages5
JournalAIDS
Volume10
Issue number11
DOIs
StatePublished - Jan 1 1996

Keywords

  • AIDS
  • Kaposi's sarcoma
  • Women

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Kaposi's sarcoma in women with AIDS'. Together they form a unique fingerprint.

Cite this