KAPs off for HIV-1 integration

Anna Figueiredo; Thomas J. Hope

doi:10.1016/j.chom.2011.05.009

KAPs off for HIV-1 integration

Anna Figueiredo, Thomas J. Hope

Cell & Developmental Biology

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Integration of reverse transcribed HIV-1 DNA into the host genome, catalyzed by HIV-1 integrase, represents an obligate step in establishing productive viral infection. Allouch et al. (2011) identify KAP1 (TRIM28) as an interaction partner of acetylated integrase. KAP1, in complex with HDAC1, represses HIV-1 integration through specific deacetylation of HIV-1 integrase.

Original language	English (US)
Pages (from-to)	447-448
Number of pages	2
Journal	Cell Host and Microbe
Volume	9
Issue number	6
DOIs	https://doi.org/10.1016/j.chom.2011.05.009
State	Published - Jun 16 2011

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.chom.2011.05.009

Cite this

@article{627119fffb5d41b48e447f6bef23f655,

title = "KAPs off for HIV-1 integration",

abstract = "Integration of reverse transcribed HIV-1 DNA into the host genome, catalyzed by HIV-1 integrase, represents an obligate step in establishing productive viral infection. Allouch et al. (2011) identify KAP1 (TRIM28) as an interaction partner of acetylated integrase. KAP1, in complex with HDAC1, represses HIV-1 integration through specific deacetylation of HIV-1 integrase.",

author = "Anna Figueiredo and Hope, {Thomas J.}",

note = "Funding Information: A.F. and T.J.H. are supported by NIH grants (P50-GM082545 and RO1 A1047770).",

year = "2011",

month = jun,

day = "16",

doi = "10.1016/j.chom.2011.05.009",

language = "English (US)",

volume = "9",

pages = "447--448",

journal = "Cell Host and Microbe",

issn = "1931-3128",

publisher = "Cell Press",

number = "6",

}

TY - JOUR

T1 - KAPs off for HIV-1 integration

AU - Figueiredo, Anna

AU - Hope, Thomas J.

N1 - Funding Information: A.F. and T.J.H. are supported by NIH grants (P50-GM082545 and RO1 A1047770).

PY - 2011/6/16

Y1 - 2011/6/16

N2 - Integration of reverse transcribed HIV-1 DNA into the host genome, catalyzed by HIV-1 integrase, represents an obligate step in establishing productive viral infection. Allouch et al. (2011) identify KAP1 (TRIM28) as an interaction partner of acetylated integrase. KAP1, in complex with HDAC1, represses HIV-1 integration through specific deacetylation of HIV-1 integrase.

AB - Integration of reverse transcribed HIV-1 DNA into the host genome, catalyzed by HIV-1 integrase, represents an obligate step in establishing productive viral infection. Allouch et al. (2011) identify KAP1 (TRIM28) as an interaction partner of acetylated integrase. KAP1, in complex with HDAC1, represses HIV-1 integration through specific deacetylation of HIV-1 integrase.

UR - http://www.scopus.com/inward/record.url?scp=79958710645&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79958710645&partnerID=8YFLogxK

U2 - 10.1016/j.chom.2011.05.009

DO - 10.1016/j.chom.2011.05.009

M3 - Short survey

C2 - 21669392

AN - SCOPUS:79958710645

VL - 9

SP - 447

EP - 448

JO - Cell Host and Microbe

JF - Cell Host and Microbe

SN - 1931-3128

IS - 6

ER -

KAPs off for HIV-1 integration

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this