KCNH2-K897T is a genetic modifier of latent congenital long-QT syndrome

Keyphrases

• Genetic Modifiers 100%
• Congenital Long QT Syndrome 100%
• KCNH2 100%
• Proband 75%
• Single nucleotide Polymorphism 50%
• Co-expression 50%
• Long QT Syndrome 50%
• Polymorphism 50%
• QT Prolongation 50%
• HERG 50%
• LQT2 50%
• KCNH2 Gene 50%
• Penetrant 25%
• Arrhythmia 25%
• Disease-causing mutations 25%
• Fluorescent Protein 25%
• Modifier Genes 25%
• Variable Penetrance 25%
• Sudden Death 25%
• White Women 25%
• Carboxyl Terminus 25%
• Ventricular Fibrillation 25%
• Current Amplitude 25%
• Expression Study 25%
• Cardiac Disease 25%
• Palpation 25%
• Cultured Human Cells 25%
• Clinical Heterogeneity 25%
• Heterologous Expression 25%
• Cardiac Arrest 25%
• Conserved Residues 25%
• Bicistronic Vector 25%
• Missense 25%
• Clinical Expression 25%
• Latent Disease 25%
• Presyncope 25%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Allele 100%
• Long QT Syndrome 100%
• Proband 75%
• Single-Nucleotide Polymorphism 50%
• HERG 50%
• Cardiac Arrest 25%
• Missense 25%
• C-Terminus 25%
• Modifier Gene 25%
• Penetrance 25%
• Current Amplitude 25%
• Heterologous Expression 25%
• Cardiac Dysrhythmia 25%
• Ventricular Fibrillation 25%
• Palpitations 25%

Neuroscience

• Long QT Syndrome 100%
• HERG 66%
• Single-Nucleotide Polymorphism 66%
• C-Terminus 33%
• Modifier Gene 33%
• Heterologous Expression 33%
• Cardiac Dysrhythmia 33%