Keloids: Prevention and Management

Douglas Mathew Sidle*, Haena Kim

*Corresponding author for this work

Research output: Contribution to journalReview article

24 Scopus citations

Abstract

Keloids result from an abnormal wound-healing process in which the normal regulatory pathways during tissue regeneration and scar remodeling are disrupted. While the pathogenesis of keloids continues to be investigated, numerous treatment options exist. Although prevention of keloid formation is the best management, early recognition of keloid formation is integral in treatment and prevention of recurrence. Surgical resection with adjuvant silicone gel sheeting or triamcinolone injection is common, but can still result in recurrence. New treatments include chemotherapeutics such as 5-fluorouracil, bleomycin, and mitomycin C. Although further clinical investigation is required for newer treatments, initial results are promising.

Original languageEnglish (US)
Pages (from-to)505-515
Number of pages11
JournalFacial plastic surgery clinics of North America
Volume19
Issue number3
DOIs
StatePublished - Aug 1 2011

Keywords

  • Hypertrophic scars
  • Keloid
  • Keloid pathophysiology
  • Scar management
  • Wound healing

ASJC Scopus subject areas

  • Surgery

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