Tumeurs du rein de l'enfant

Translated title of the contribution: Kidney tumors in childhood

Elizabeth J Perlman, L. Boccon-Gibod*

*Corresponding author for this work

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Types of renal tumors arising in children are different from those occuring in adults. Nephroblastoma is the most common (85%) with a clinical outcome which has dramatically improved in the last 30 years. Current classifications are aimed at better adaptation of treatment to each individual case, reducing iatrogenic complications without impairing total cure. Amongst entities which have been recently described or are better known we can find juvenile carcinoma associated with Xp11.2 translocation, renal medullary carcinoma, metanephric tumors, etc. Role of molecular cytogenetics is increasing for classification (and treatment) and this should always be kept in mind when dealing a fresh specimen of childhood renal tumor.

Original languageFrench
Pages (from-to)516-535
Number of pages20
JournalAnnales de Pathologie
Volume24
Issue number6
StatePublished - Jan 1 2004

Fingerprint

Kidney
Neoplasms
Medullary Carcinoma
Wilms Tumor
Cytogenetics
Carcinoma
Therapeutics

Keywords

  • Anaplasia
  • Clear cell sarcoma of the kidney
  • Cystic tumor of the kidney
  • Mesoblastic nephroma
  • Metanephric adenoma
  • Metanephric stromal tumor
  • Nephroblastoma
  • Renal cell carcinoma
  • Renal rhabdoid
  • Renal tumor
  • TFE-3 gene fusion

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Perlman, E. J., & Boccon-Gibod, L. (2004). Tumeurs du rein de l'enfant. Annales de Pathologie, 24(6), 516-535.
Perlman, Elizabeth J ; Boccon-Gibod, L. / Tumeurs du rein de l'enfant. In: Annales de Pathologie. 2004 ; Vol. 24, No. 6. pp. 516-535.
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Perlman, EJ & Boccon-Gibod, L 2004, 'Tumeurs du rein de l'enfant', Annales de Pathologie, vol. 24, no. 6, pp. 516-535.

Tumeurs du rein de l'enfant. / Perlman, Elizabeth J; Boccon-Gibod, L.

In: Annales de Pathologie, Vol. 24, No. 6, 01.01.2004, p. 516-535.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Tumeurs du rein de l'enfant

AU - Perlman, Elizabeth J

AU - Boccon-Gibod, L.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Types of renal tumors arising in children are different from those occuring in adults. Nephroblastoma is the most common (85%) with a clinical outcome which has dramatically improved in the last 30 years. Current classifications are aimed at better adaptation of treatment to each individual case, reducing iatrogenic complications without impairing total cure. Amongst entities which have been recently described or are better known we can find juvenile carcinoma associated with Xp11.2 translocation, renal medullary carcinoma, metanephric tumors, etc. Role of molecular cytogenetics is increasing for classification (and treatment) and this should always be kept in mind when dealing a fresh specimen of childhood renal tumor.

AB - Types of renal tumors arising in children are different from those occuring in adults. Nephroblastoma is the most common (85%) with a clinical outcome which has dramatically improved in the last 30 years. Current classifications are aimed at better adaptation of treatment to each individual case, reducing iatrogenic complications without impairing total cure. Amongst entities which have been recently described or are better known we can find juvenile carcinoma associated with Xp11.2 translocation, renal medullary carcinoma, metanephric tumors, etc. Role of molecular cytogenetics is increasing for classification (and treatment) and this should always be kept in mind when dealing a fresh specimen of childhood renal tumor.

KW - Anaplasia

KW - Clear cell sarcoma of the kidney

KW - Cystic tumor of the kidney

KW - Mesoblastic nephroma

KW - Metanephric adenoma

KW - Metanephric stromal tumor

KW - Nephroblastoma

KW - Renal cell carcinoma

KW - Renal rhabdoid

KW - Renal tumor

KW - TFE-3 gene fusion

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M3 - Review article

VL - 24

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Perlman EJ, Boccon-Gibod L. Tumeurs du rein de l'enfant. Annales de Pathologie. 2004 Jan 1;24(6):516-535.