Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials: A mediational model

Sharon Manne*, Deborah Kashy, Terrance Albrecht, Yu Ning Wong, Anne Lederman Flamm, Al B Benson III, Suzanne M. Miller, Linda Fleisher, Joanne Buzaglo, Nancy Roach, Michael Katz, Eric Ross, Michael Collins, David Poole, Stephanie Raivitch, Dawn M. Miller, Tyler G. Kinzy, Tasnuva Liu, Neal J. Meropol

*Corresponding author for this work

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective. This study used the Ottawa Decision Support Framework to evaluate a model examining associations between clinical trial knowledge, attitudinal barriers to participating in clinical trials, clinical trial self-efficacy, and clinical trial preparedness among 1256 cancer patients seen for their first outpatient consultation at a cancer center. As an exploratory aim, moderator effects for gender, race/ethnicity, education, and metastatic status on associations in the model were evaluated. Methods. Patients completed measures of cancer clinical trial knowledge, attitudinal barriers, self-efficacy, and preparedness. Structural equation modeling (SEM) was conducted to evaluate whether self-efficacy mediated the association between knowledge and barriers with preparedness. Results. The SEM explained 26% of the variance in cancer clinical trial preparedness. Self-efficacy mediated the associations between attitudinal barriers and preparedness, but self-efficacy did not mediate the knowledge-preparedness relationship. Conclusions. Findings partially support the Ottawa Decision Support Framework and suggest that assessing patients' level of self-efficacy may be just as important as evaluating their knowledge and attitudes about cancer clinical trials.

Original languageEnglish (US)
Pages (from-to)454-463
Number of pages10
JournalMedical Decision Making
Volume34
Issue number4
DOIs
StatePublished - Jan 1 2014

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Self Efficacy
Clinical Trials
Neoplasms
Outpatients
Referral and Consultation
Education

Keywords

  • Ottawa Decision Support Framework
  • cancer clinical trials
  • cancer patients

ASJC Scopus subject areas

  • Health Policy

Cite this

Manne, Sharon ; Kashy, Deborah ; Albrecht, Terrance ; Wong, Yu Ning ; Flamm, Anne Lederman ; Benson III, Al B ; Miller, Suzanne M. ; Fleisher, Linda ; Buzaglo, Joanne ; Roach, Nancy ; Katz, Michael ; Ross, Eric ; Collins, Michael ; Poole, David ; Raivitch, Stephanie ; Miller, Dawn M. ; Kinzy, Tyler G. ; Liu, Tasnuva ; Meropol, Neal J. / Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials : A mediational model. In: Medical Decision Making. 2014 ; Vol. 34, No. 4. pp. 454-463.
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title = "Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials: A mediational model",
abstract = "Objective. This study used the Ottawa Decision Support Framework to evaluate a model examining associations between clinical trial knowledge, attitudinal barriers to participating in clinical trials, clinical trial self-efficacy, and clinical trial preparedness among 1256 cancer patients seen for their first outpatient consultation at a cancer center. As an exploratory aim, moderator effects for gender, race/ethnicity, education, and metastatic status on associations in the model were evaluated. Methods. Patients completed measures of cancer clinical trial knowledge, attitudinal barriers, self-efficacy, and preparedness. Structural equation modeling (SEM) was conducted to evaluate whether self-efficacy mediated the association between knowledge and barriers with preparedness. Results. The SEM explained 26{\%} of the variance in cancer clinical trial preparedness. Self-efficacy mediated the associations between attitudinal barriers and preparedness, but self-efficacy did not mediate the knowledge-preparedness relationship. Conclusions. Findings partially support the Ottawa Decision Support Framework and suggest that assessing patients' level of self-efficacy may be just as important as evaluating their knowledge and attitudes about cancer clinical trials.",
keywords = "Ottawa Decision Support Framework, cancer clinical trials, cancer patients",
author = "Sharon Manne and Deborah Kashy and Terrance Albrecht and Wong, {Yu Ning} and Flamm, {Anne Lederman} and {Benson III}, {Al B} and Miller, {Suzanne M.} and Linda Fleisher and Joanne Buzaglo and Nancy Roach and Michael Katz and Eric Ross and Michael Collins and David Poole and Stephanie Raivitch and Miller, {Dawn M.} and Kinzy, {Tyler G.} and Tasnuva Liu and Meropol, {Neal J.}",
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Manne, S, Kashy, D, Albrecht, T, Wong, YN, Flamm, AL, Benson III, AB, Miller, SM, Fleisher, L, Buzaglo, J, Roach, N, Katz, M, Ross, E, Collins, M, Poole, D, Raivitch, S, Miller, DM, Kinzy, TG, Liu, T & Meropol, NJ 2014, 'Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials: A mediational model', Medical Decision Making, vol. 34, no. 4, pp. 454-463. https://doi.org/10.1177/0272989X13511704

Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials : A mediational model. / Manne, Sharon; Kashy, Deborah; Albrecht, Terrance; Wong, Yu Ning; Flamm, Anne Lederman; Benson III, Al B; Miller, Suzanne M.; Fleisher, Linda; Buzaglo, Joanne; Roach, Nancy; Katz, Michael; Ross, Eric; Collins, Michael; Poole, David; Raivitch, Stephanie; Miller, Dawn M.; Kinzy, Tyler G.; Liu, Tasnuva; Meropol, Neal J.

In: Medical Decision Making, Vol. 34, No. 4, 01.01.2014, p. 454-463.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials

T2 - A mediational model

AU - Manne, Sharon

AU - Kashy, Deborah

AU - Albrecht, Terrance

AU - Wong, Yu Ning

AU - Flamm, Anne Lederman

AU - Benson III, Al B

AU - Miller, Suzanne M.

AU - Fleisher, Linda

AU - Buzaglo, Joanne

AU - Roach, Nancy

AU - Katz, Michael

AU - Ross, Eric

AU - Collins, Michael

AU - Poole, David

AU - Raivitch, Stephanie

AU - Miller, Dawn M.

AU - Kinzy, Tyler G.

AU - Liu, Tasnuva

AU - Meropol, Neal J.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Objective. This study used the Ottawa Decision Support Framework to evaluate a model examining associations between clinical trial knowledge, attitudinal barriers to participating in clinical trials, clinical trial self-efficacy, and clinical trial preparedness among 1256 cancer patients seen for their first outpatient consultation at a cancer center. As an exploratory aim, moderator effects for gender, race/ethnicity, education, and metastatic status on associations in the model were evaluated. Methods. Patients completed measures of cancer clinical trial knowledge, attitudinal barriers, self-efficacy, and preparedness. Structural equation modeling (SEM) was conducted to evaluate whether self-efficacy mediated the association between knowledge and barriers with preparedness. Results. The SEM explained 26% of the variance in cancer clinical trial preparedness. Self-efficacy mediated the associations between attitudinal barriers and preparedness, but self-efficacy did not mediate the knowledge-preparedness relationship. Conclusions. Findings partially support the Ottawa Decision Support Framework and suggest that assessing patients' level of self-efficacy may be just as important as evaluating their knowledge and attitudes about cancer clinical trials.

AB - Objective. This study used the Ottawa Decision Support Framework to evaluate a model examining associations between clinical trial knowledge, attitudinal barriers to participating in clinical trials, clinical trial self-efficacy, and clinical trial preparedness among 1256 cancer patients seen for their first outpatient consultation at a cancer center. As an exploratory aim, moderator effects for gender, race/ethnicity, education, and metastatic status on associations in the model were evaluated. Methods. Patients completed measures of cancer clinical trial knowledge, attitudinal barriers, self-efficacy, and preparedness. Structural equation modeling (SEM) was conducted to evaluate whether self-efficacy mediated the association between knowledge and barriers with preparedness. Results. The SEM explained 26% of the variance in cancer clinical trial preparedness. Self-efficacy mediated the associations between attitudinal barriers and preparedness, but self-efficacy did not mediate the knowledge-preparedness relationship. Conclusions. Findings partially support the Ottawa Decision Support Framework and suggest that assessing patients' level of self-efficacy may be just as important as evaluating their knowledge and attitudes about cancer clinical trials.

KW - Ottawa Decision Support Framework

KW - cancer clinical trials

KW - cancer patients

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