A number of KLF family members are known to play important roles in the regulation of proliferation, differentiation, and development of the gastrointestinal tract. Of these, KLF4 (previously known as GKLF or EZF) and KLF5 (previously known as IKLF or BTEB2) have been the most extensively studied. In this chapter, we review the expression patterns and established functions for KLF family members in the gastrointestinal tract and offer insight into possible future areas of investigation of the KLFs in gastrointestinal differentiation and development.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)