Label-free imaging of single neuron activities by stimulated Raman scattering

Delong Zhang, Hyeon Jeong Lee, Pei Yu Shih, Ryan E. Drenan, Ji Xin Cheng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report the observation of single neuron activities by spectral focusing stimulated Raman scattering (SRS) microscopy. Changes in SRS signal intensity in live neurons correlate to action potentials indicated by fluorescent calcium indicator.

Original languageEnglish (US)
Title of host publication2015 Conference on Lasers and Electro-Optics, CLEO 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Volume2015-August
ISBN (Electronic)9781557529688
StatePublished - Aug 10 2015
EventConference on Lasers and Electro-Optics, CLEO 2015 - San Jose, United States
Duration: May 10 2015May 15 2015

Other

OtherConference on Lasers and Electro-Optics, CLEO 2015
Country/TerritoryUnited States
CitySan Jose
Period5/10/155/15/15

Keywords

  • Calcium
  • Fluorescence
  • Image resolution
  • Microscopy
  • Neurons
  • Raman scattering

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials

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