Laboratory diagnosis of neonatal herpes simplex virus infections

William J. Muller, Xiaotian Zheng*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Herpes simplex virus (HSV) is a common and often benign infection in humans; although it less commonly affects newborns, infection in this age group can be devastating. Newborns often present with nonspecific clinical findings, making timely and accurate diagnosis of infection critical. A wide variety of tests are available for detecting herpes simplex virus infection, but only a subset are useful and validated in the newborn population. The current review summarizes available diagnostic testing for neonatal disease, including discussing limitations, unmet needs, and emerging data on molecular testing methods.

Original languageEnglish (US)
Article numbere01460-18
JournalJournal of clinical microbiology
Issue number5
StatePublished - May 2019


  • Diagnostics
  • Herpes simplex virus
  • Neonates

ASJC Scopus subject areas

  • Microbiology (medical)


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