Lack of association of NALCN genetic variants with schizophrenia

Renan P. Souza*, Daniela V F Rosa, Marco A. Romano-Silva, Mei Zhen, Herbert Y. Meltzer, Jeffrey A. Lieberman, Gary Remington, James L. Kennedy, Albert H C Wong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

NALCN (sodium leak channel, non-selective) is located on chromosome 13q (suggested linkage region for schizophrenia). We analyzed 21 polymorphisms in 464 schizophrenia subjects, 220 controls subjects and 119 small nuclear families. We observed nominal association with rs9518320 and rs9518331, suggesting that NALCN is not related to schizophrenia risk.

Original languageEnglish (US)
Pages (from-to)450-452
Number of pages3
JournalPsychiatry Research
Volume185
Issue number3
DOIs
StatePublished - Feb 28 2011

Keywords

  • Genetic association
  • NALCN
  • Schizophrenia
  • VGCNL

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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