Lack of consensus in the diagnosis and treatment for ocular tuberculosis among uveitis specialists

Susan M. Lou, Kelly L. Larkin, Kevin Winthrop, James T. Rosenbaum*, Massimo Accorinti, Sofia Androudi, Lourdes Arellanes, Matthias Becker, Bahram Bodaghi, Soon Phaik Chee, Smet De Smet, D. Marc, Michal Kramer, Genevieve Larkin, Sue Lightman, Lyndell Lim, Juan Lopez, Friederike Mackensen, Peter McCluskey, Cristina MuccioliA. Okada Annabelle, Narciss Okhravi, Daniel Vasconcelos-Santos, Peter McCluskey Zamir, Manfred Zierhut, Nisha Acharya, Andrea Birnbaum, Nicholas J. Butler, David Callanan, Emmett Cunningham, Sam Dahr, Janet L. Davis, Larissa Derzko-Dzulynsky, James Dunn, Albert O. Edwards, Lisa Faia, Naomi Falk, Farzin Forooghian, C. Stephen Foster, Alan H. Friedman, Sunir Garg, Paul Gaudio, Ronald Gentile, Debra Goldstein, Douglas Jabs, Glen Jaffe, Kashyap Kansupada, Henry Kaplan, Sanjay Kedhar, John H. Kempen, Uveitis Specialists Study Group

*Corresponding author for this work

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Purpose: To assess the approach of specialists to ocular tuberculosis (TB). Methods: The American Uveitis Society (AUS) Listserv was surveyed using two clinical cases and general questions. Results: Of 196 members, 87 responded (44.4%), of whom 64 were affiliated with practices in North America, while 23 were outside of North America. The survey provided normative data on how physicians evaluate patients with uveitis as well as opinions about ocular TB. Responses varied widely on such issues as (1) the pretest probability that a patient with granulomatous panuveitis had TB uveitis (range 1-75%) or that a patient with a risk factor for TB had ocular TB (range 0-90%); (2) the optimal duration of anti-TB therapy; and (3) whether therapy should be discontinued after 2 months in nonresponders. Conclusions: Consensus is lacking among uveitis specialists for the diagnosis or management of ocular TB.

Original languageEnglish (US)
Pages (from-to)25-31
Number of pages7
JournalOcular Immunology and Inflammation
Volume23
Issue number1
DOIs
StatePublished - Feb 1 2015

Keywords

  • Post-test probability
  • Pretest probability
  • Tuberculosis
  • Uveitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

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    Lou, S. M., Larkin, K. L., Winthrop, K., Rosenbaum, J. T., Accorinti, M., Androudi, S., Arellanes, L., Becker, M., Bodaghi, B., Chee, S. P., De Smet, S., Marc, D., Kramer, M., Larkin, G., Lightman, S., Lim, L., Lopez, J., Mackensen, F., McCluskey, P., ... Uveitis Specialists Study Group (2015). Lack of consensus in the diagnosis and treatment for ocular tuberculosis among uveitis specialists. Ocular Immunology and Inflammation, 23(1), 25-31. https://doi.org/10.3109/09273948.2014.926936