Lack of effect of tricyclic antidepressants on serum prolactin levels

Herbert Y. Meltzer; Songkait Piyakalmala; Paul Schyve; Victor S. Fang

doi:10.1007/BF00431738

Lack of effect of tricyclic antidepressants on serum prolactin levels

Herbert Y. Meltzer^*, Songkait Piyakalmala, Paul Schyve, Victor S. Fang

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

A previous report indicated that the tricyclic antidepressants imipramine and amitriptyline markedly increased plasma prolactin levels in man. We found no increases after acute or chronic treatment with either drug in usual clinical doses. The results indicate that blockade of serotonin reuptake does not affect basal prolactin levels in man.

Original language	English (US)
Pages (from-to)	185-187
Number of pages	3
Journal	Psychopharmacology
Volume	51
Issue number	2
DOIs	https://doi.org/10.1007/BF00431738
State	Published - Jan 1 1977

Keywords

Amitriptyline
Imipramine
Prolactin
Tricyclic antidepressants

ASJC Scopus subject areas

Pharmacology

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10.1007/BF00431738

Cite this

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title = "Lack of effect of tricyclic antidepressants on serum prolactin levels",

abstract = "A previous report indicated that the tricyclic antidepressants imipramine and amitriptyline markedly increased plasma prolactin levels in man. We found no increases after acute or chronic treatment with either drug in usual clinical doses. The results indicate that blockade of serotonin reuptake does not affect basal prolactin levels in man.",

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AU - Meltzer, Herbert Y.

AU - Piyakalmala, Songkait

AU - Schyve, Paul

AU - Fang, Victor S.

PY - 1977/1/1

Y1 - 1977/1/1

N2 - A previous report indicated that the tricyclic antidepressants imipramine and amitriptyline markedly increased plasma prolactin levels in man. We found no increases after acute or chronic treatment with either drug in usual clinical doses. The results indicate that blockade of serotonin reuptake does not affect basal prolactin levels in man.

AB - A previous report indicated that the tricyclic antidepressants imipramine and amitriptyline markedly increased plasma prolactin levels in man. We found no increases after acute or chronic treatment with either drug in usual clinical doses. The results indicate that blockade of serotonin reuptake does not affect basal prolactin levels in man.

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KW - Imipramine

KW - Prolactin

KW - Tricyclic antidepressants

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Lack of effect of tricyclic antidepressants on serum prolactin levels

Abstract

Keywords

ASJC Scopus subject areas

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