Lamina muscularis propria thickness of renal pelvis predicts radiological outcome of surgical correction of ureteropelvic junction obstruction

Won Han Sang Won Han, M. Maizels, P. M. Chou, S. K. Fernbach, E. Y. Cheng, P. D. Furness*

*Corresponding author for this work

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Purpose: We examine if there is a relationship between the histopathology of the renal pelvis and postoperative radiological findings in children with ureteropelvic junction obstruction. Materials and Methods: The records of 220 patients who underwent pyeloplasty for isolated ureteropelvic junction obstruction between 1988 and 1996 were retrospectively reviewed, and 41 (42 kidneys) were identified who had adequate histological specimens and postoperative radiographic studies (ultrasonography and/or well tempered renogram) for examination. Histological features of the lamina muscularis propria from the renal pelvis were correlated with the radiographic outcome after pyeloplasty. Results: Lamina muscularis propria thickness of the renal pelvis correlated significantly with radiological improvement. All kidneys with renal pelvic lamina muscularis propria thickness less than 250μm. showed radiological improvement at 3 to 6 months postoperatively, those with thickness between 250 and 350 μm. had improvement at 9 months and those with lamina thickness greater than 350 μm. had a significantly worse outcome at all observation points. At 3 and 6 months postoperatively 16 of 30 (53%) and 23 of 34 (68%) children with radiological improvement had a mean lamina muscularis propria thickness of 252 ± 131.5 μm. and 263 ± 122.8 μm., respectively, while the remaining unimproved 14 and 12 patients had a mean thickness of 374 ± 64.3 μm. (p <0.01) 372 ± 66.1 μm. (p <0.05), respectively. Conclusions: The lamina muscularis propria thickness of the renal pelvic wall can provide insight to the expected time of postoperative improvement on radiological studies in children with ureteropelvic junction obstruction.

Original languageEnglish (US)
Pages (from-to)1648-1651
Number of pages4
JournalJournal of Urology
Volume165
Issue number5 I
StatePublished - May 17 2001

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Kidney Pelvis
Mucous Membrane
Kidney
Ultrasonography
Observation

Keywords

  • Child
  • Hydronephrosis
  • Kidney pelvis
  • Ureteral obstruction

ASJC Scopus subject areas

  • Urology

Cite this

@article{6b9546e906a043cd9b343124fccff116,
title = "Lamina muscularis propria thickness of renal pelvis predicts radiological outcome of surgical correction of ureteropelvic junction obstruction",
abstract = "Purpose: We examine if there is a relationship between the histopathology of the renal pelvis and postoperative radiological findings in children with ureteropelvic junction obstruction. Materials and Methods: The records of 220 patients who underwent pyeloplasty for isolated ureteropelvic junction obstruction between 1988 and 1996 were retrospectively reviewed, and 41 (42 kidneys) were identified who had adequate histological specimens and postoperative radiographic studies (ultrasonography and/or well tempered renogram) for examination. Histological features of the lamina muscularis propria from the renal pelvis were correlated with the radiographic outcome after pyeloplasty. Results: Lamina muscularis propria thickness of the renal pelvis correlated significantly with radiological improvement. All kidneys with renal pelvic lamina muscularis propria thickness less than 250μm. showed radiological improvement at 3 to 6 months postoperatively, those with thickness between 250 and 350 μm. had improvement at 9 months and those with lamina thickness greater than 350 μm. had a significantly worse outcome at all observation points. At 3 and 6 months postoperatively 16 of 30 (53{\%}) and 23 of 34 (68{\%}) children with radiological improvement had a mean lamina muscularis propria thickness of 252 ± 131.5 μm. and 263 ± 122.8 μm., respectively, while the remaining unimproved 14 and 12 patients had a mean thickness of 374 ± 64.3 μm. (p <0.01) 372 ± 66.1 μm. (p <0.05), respectively. Conclusions: The lamina muscularis propria thickness of the renal pelvic wall can provide insight to the expected time of postoperative improvement on radiological studies in children with ureteropelvic junction obstruction.",
keywords = "Child, Hydronephrosis, Kidney pelvis, Ureteral obstruction",
author = "{Sang Won Han}, {Won Han} and M. Maizels and Chou, {P. M.} and Fernbach, {S. K.} and Cheng, {E. Y.} and Furness, {P. D.}",
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Lamina muscularis propria thickness of renal pelvis predicts radiological outcome of surgical correction of ureteropelvic junction obstruction. / Sang Won Han, Won Han; Maizels, M.; Chou, P. M.; Fernbach, S. K.; Cheng, E. Y.; Furness, P. D.

In: Journal of Urology, Vol. 165, No. 5 I, 17.05.2001, p. 1648-1651.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Lamina muscularis propria thickness of renal pelvis predicts radiological outcome of surgical correction of ureteropelvic junction obstruction

AU - Sang Won Han, Won Han

AU - Maizels, M.

AU - Chou, P. M.

AU - Fernbach, S. K.

AU - Cheng, E. Y.

AU - Furness, P. D.

PY - 2001/5/17

Y1 - 2001/5/17

N2 - Purpose: We examine if there is a relationship between the histopathology of the renal pelvis and postoperative radiological findings in children with ureteropelvic junction obstruction. Materials and Methods: The records of 220 patients who underwent pyeloplasty for isolated ureteropelvic junction obstruction between 1988 and 1996 were retrospectively reviewed, and 41 (42 kidneys) were identified who had adequate histological specimens and postoperative radiographic studies (ultrasonography and/or well tempered renogram) for examination. Histological features of the lamina muscularis propria from the renal pelvis were correlated with the radiographic outcome after pyeloplasty. Results: Lamina muscularis propria thickness of the renal pelvis correlated significantly with radiological improvement. All kidneys with renal pelvic lamina muscularis propria thickness less than 250μm. showed radiological improvement at 3 to 6 months postoperatively, those with thickness between 250 and 350 μm. had improvement at 9 months and those with lamina thickness greater than 350 μm. had a significantly worse outcome at all observation points. At 3 and 6 months postoperatively 16 of 30 (53%) and 23 of 34 (68%) children with radiological improvement had a mean lamina muscularis propria thickness of 252 ± 131.5 μm. and 263 ± 122.8 μm., respectively, while the remaining unimproved 14 and 12 patients had a mean thickness of 374 ± 64.3 μm. (p <0.01) 372 ± 66.1 μm. (p <0.05), respectively. Conclusions: The lamina muscularis propria thickness of the renal pelvic wall can provide insight to the expected time of postoperative improvement on radiological studies in children with ureteropelvic junction obstruction.

AB - Purpose: We examine if there is a relationship between the histopathology of the renal pelvis and postoperative radiological findings in children with ureteropelvic junction obstruction. Materials and Methods: The records of 220 patients who underwent pyeloplasty for isolated ureteropelvic junction obstruction between 1988 and 1996 were retrospectively reviewed, and 41 (42 kidneys) were identified who had adequate histological specimens and postoperative radiographic studies (ultrasonography and/or well tempered renogram) for examination. Histological features of the lamina muscularis propria from the renal pelvis were correlated with the radiographic outcome after pyeloplasty. Results: Lamina muscularis propria thickness of the renal pelvis correlated significantly with radiological improvement. All kidneys with renal pelvic lamina muscularis propria thickness less than 250μm. showed radiological improvement at 3 to 6 months postoperatively, those with thickness between 250 and 350 μm. had improvement at 9 months and those with lamina thickness greater than 350 μm. had a significantly worse outcome at all observation points. At 3 and 6 months postoperatively 16 of 30 (53%) and 23 of 34 (68%) children with radiological improvement had a mean lamina muscularis propria thickness of 252 ± 131.5 μm. and 263 ± 122.8 μm., respectively, while the remaining unimproved 14 and 12 patients had a mean thickness of 374 ± 64.3 μm. (p <0.01) 372 ± 66.1 μm. (p <0.05), respectively. Conclusions: The lamina muscularis propria thickness of the renal pelvic wall can provide insight to the expected time of postoperative improvement on radiological studies in children with ureteropelvic junction obstruction.

KW - Child

KW - Hydronephrosis

KW - Kidney pelvis

KW - Ureteral obstruction

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M3 - Article

VL - 165

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EP - 1651

JO - Journal of Urology

JF - Journal of Urology

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