Langerhans cell histiocytosis and dermatophytosis

Anita S. Pakula, Amy S. Paller*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, scaling and erythema may also be confused with tinea capitis. We describe four patients who had LCH and documented dermatophyte infection versus colonization of the scalp. Fungal cultures should be considered in patients who have LCH with scalp involvement who do not respond to standard treatment; similarly, it may be appropriate to obtain a skin biopsy specimen from patients with recalcitrant tinea capitis to rule out the presence of underlying LCH.

Original languageEnglish (US)
Pages (from-to)340-343
Number of pages4
JournalJournal of the American Academy of Dermatology
Issue number2
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Dermatology


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