Language and alexithymia

Evidence for the role of the inferior frontal gyrus in acquired alexithymia

Hannah Hobson*, Jeremy Hogeveen, Rebecca Brewer, Caroline Catmur, Barry Gordon, Frank Krueger, Aileen Chau, Geoffrey Bird, Jordan Henry Grafman

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The clinical relevance of alexithymia, a condition associated with difficulties identifying and describing one's own emotion, is becoming ever more apparent. Increased rates of alexithymia are observed in multiple psychiatric conditions, and also in neurological conditions resulting from both organic and traumatic brain injury. The presence of alexithymia in these conditions predicts poorer regulation of one's emotions, decreased treatment response, and increased burden on carers. While clinically important, the aetiology of alexithymia is still a matter of debate, with several authors arguing for multiple ‘routes’ to impaired understanding of one's own emotions, which may or may not result in distinct subtypes of alexithymia. While previous studies support the role of impaired interoception (perceiving bodily states) in the development of alexithymia, the current study assessed whether acquired language impairment following traumatic brain injury, and damage to language regions, may also be associated with an increased risk of alexithymia. Within a sample of 129 participants with penetrating brain injury and 33 healthy controls, neuropsychological testing revealed that deficits in a non-emotional language task, object naming, were associated with alexithymia, specifically with difficulty identifying one's own emotions. Both region-of-interest and whole-brain lesion analyses revealed that damage to language regions in the inferior frontal gyrus was associated with the presence of both this language impairment and alexithymia. These results are consistent with a framework for acquired alexithymia that incorporates both interoceptive and language processes, and support the idea that brain injury may result in alexithymia via impairment in any one of a number of more basic processes.

Original languageEnglish (US)
Pages (from-to)229-240
Number of pages12
JournalNeuropsychologia
Volume111
DOIs
StatePublished - Mar 1 2018

Fingerprint

Affective Symptoms
Prefrontal Cortex
Language
Emotions
Penetrating Head Injuries
Brain Injuries
Caregivers
Psychiatry

Keywords

  • Alexithymia
  • Anterior insula
  • Inferior frontal gyrus
  • Language
  • Traumatic brain injury

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

Cite this

Hobson, Hannah ; Hogeveen, Jeremy ; Brewer, Rebecca ; Catmur, Caroline ; Gordon, Barry ; Krueger, Frank ; Chau, Aileen ; Bird, Geoffrey ; Grafman, Jordan Henry. / Language and alexithymia : Evidence for the role of the inferior frontal gyrus in acquired alexithymia. In: Neuropsychologia. 2018 ; Vol. 111. pp. 229-240.
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Language and alexithymia : Evidence for the role of the inferior frontal gyrus in acquired alexithymia. / Hobson, Hannah; Hogeveen, Jeremy; Brewer, Rebecca; Catmur, Caroline; Gordon, Barry; Krueger, Frank; Chau, Aileen; Bird, Geoffrey; Grafman, Jordan Henry.

In: Neuropsychologia, Vol. 111, 01.03.2018, p. 229-240.

Research output: Contribution to journalArticle

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