Language disturbances in corticobasal degeneration

C. M. Frattali, J. Grafman, N. Patronas, F. Makhlouf, Irene Litvan*

*Corresponding author for this work

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

To characterize the language deficits in corticobasal de generation (CBD) and their relation to neuroradiologic findings, the authors administered a standardized battery of neurobehavioral tests and performed MRI studies on 15 patients with CBD. Eight patients (53%) had classifiable aphasias, including anomic, Broca's and transcortical motor aphasias. The aphasias were associated primarily with left frontal and parietal cortical damage and subcortical white matter and corpus callosum abnormalities. Our findings demonstrate that language disturbances in CBD are more frequent than previously considered.

Original languageEnglish (US)
Pages (from-to)990-992
Number of pages3
JournalNeurology
Volume54
Issue number4
DOIs
StatePublished - Feb 22 2000

Fingerprint

Language
Anomia
Broca Aphasia
Corpus Callosum
Aphasia
White Matter

Keywords

  • Aphasia
  • Corticobasal degeneration
  • Language disturbances

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Frattali, C. M., Grafman, J., Patronas, N., Makhlouf, F., & Litvan, I. (2000). Language disturbances in corticobasal degeneration. Neurology, 54(4), 990-992. https://doi.org/10.1212/WNL.54.4.990
Frattali, C. M. ; Grafman, J. ; Patronas, N. ; Makhlouf, F. ; Litvan, Irene. / Language disturbances in corticobasal degeneration. In: Neurology. 2000 ; Vol. 54, No. 4. pp. 990-992.
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Frattali, CM, Grafman, J, Patronas, N, Makhlouf, F & Litvan, I 2000, 'Language disturbances in corticobasal degeneration', Neurology, vol. 54, no. 4, pp. 990-992. https://doi.org/10.1212/WNL.54.4.990

Language disturbances in corticobasal degeneration. / Frattali, C. M.; Grafman, J.; Patronas, N.; Makhlouf, F.; Litvan, Irene.

In: Neurology, Vol. 54, No. 4, 22.02.2000, p. 990-992.

Research output: Contribution to journalArticle

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T1 - Language disturbances in corticobasal degeneration

AU - Frattali, C. M.

AU - Grafman, J.

AU - Patronas, N.

AU - Makhlouf, F.

AU - Litvan, Irene

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Y1 - 2000/2/22

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AB - To characterize the language deficits in corticobasal de generation (CBD) and their relation to neuroradiologic findings, the authors administered a standardized battery of neurobehavioral tests and performed MRI studies on 15 patients with CBD. Eight patients (53%) had classifiable aphasias, including anomic, Broca's and transcortical motor aphasias. The aphasias were associated primarily with left frontal and parietal cortical damage and subcortical white matter and corpus callosum abnormalities. Our findings demonstrate that language disturbances in CBD are more frequent than previously considered.

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Frattali CM, Grafman J, Patronas N, Makhlouf F, Litvan I. Language disturbances in corticobasal degeneration. Neurology. 2000 Feb 22;54(4):990-992. https://doi.org/10.1212/WNL.54.4.990