Language disturbances in corticobasal degeneration

C. M. Frattali, J. Grafman, N. Patronas, F. Makhlouf, Irene Litvan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

To characterize the language deficits in corticobasal de generation (CBD) and their relation to neuroradiologic findings, the authors administered a standardized battery of neurobehavioral tests and performed MRI studies on 15 patients with CBD. Eight patients (53%) had classifiable aphasias, including anomic, Broca's and transcortical motor aphasias. The aphasias were associated primarily with left frontal and parietal cortical damage and subcortical white matter and corpus callosum abnormalities. Our findings demonstrate that language disturbances in CBD are more frequent than previously considered.

Original languageEnglish (US)
Pages (from-to)990-992
Number of pages3
JournalNeurology
Volume54
Issue number4
DOIs
StatePublished - Feb 22 2000

Keywords

  • Aphasia
  • Corticobasal degeneration
  • Language disturbances

ASJC Scopus subject areas

  • Clinical Neurology

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