Abstract
The diaphragm is both a muscular and tendinous tissue that begins to bear mechanical pressure from the abdominal vis- cera during the tenth week of life. Abnormal diaphragmatic development can lead to large congenital diaphragmatic hernias present at birth, while other smaller areas of dia- phragmatic weakness can enlarge over time and become apparent later in life. Hiatal hernias result from a widening of the diaphragmatic crura and a weakening of the phre- noesophageal membrane. This results in a protrusion of a hernia sac containing intra-abdominal organs through the diaphragmatic hiatus and into the mediastinum. The preva- lence of large hiatal hernias increases with age, suggesting that environmental and tissue-aging factors are involved in the pathophysiology. In addition, there is a positive asso- ciation between the presence of hiatal and inguinal hernias, suggesting either a genetic predisposition affecting tissue integrity or some other common factor, such as increased intra-abdominal pressure.
| Original language | English (US) |
|---|---|
| Title of host publication | Operative Thoracic Surgery, Sixth Edition |
| Publisher | CRC Press |
| Pages | 411-418 |
| Number of pages | 8 |
| ISBN (Electronic) | 9781482299588 |
| ISBN (Print) | 9781482299571 |
| DOIs | |
| State | Published - Jan 1 2017 |
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ASJC Scopus subject areas
- Medicine(all)
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Laparoscopic large hiatus hernia repair. / Nagle, Alexander P; Chow, Geoffrey S.; Soper, Nathaniel J.
Operative Thoracic Surgery, Sixth Edition. CRC Press, 2017. p. 411-418.Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Laparoscopic large hiatus hernia repair
AU - Nagle, Alexander P
AU - Chow, Geoffrey S.
AU - Soper, Nathaniel J
PY - 2017/1/1
Y1 - 2017/1/1
N2 - The diaphragm is both a muscular and tendinous tissue that begins to bear mechanical pressure from the abdominal vis- cera during the tenth week of life. Abnormal diaphragmatic development can lead to large congenital diaphragmatic hernias present at birth, while other smaller areas of dia- phragmatic weakness can enlarge over time and become apparent later in life. Hiatal hernias result from a widening of the diaphragmatic crura and a weakening of the phre- noesophageal membrane. This results in a protrusion of a hernia sac containing intra-abdominal organs through the diaphragmatic hiatus and into the mediastinum. The preva- lence of large hiatal hernias increases with age, suggesting that environmental and tissue-aging factors are involved in the pathophysiology. In addition, there is a positive asso- ciation between the presence of hiatal and inguinal hernias, suggesting either a genetic predisposition affecting tissue integrity or some other common factor, such as increased intra-abdominal pressure.
AB - The diaphragm is both a muscular and tendinous tissue that begins to bear mechanical pressure from the abdominal vis- cera during the tenth week of life. Abnormal diaphragmatic development can lead to large congenital diaphragmatic hernias present at birth, while other smaller areas of dia- phragmatic weakness can enlarge over time and become apparent later in life. Hiatal hernias result from a widening of the diaphragmatic crura and a weakening of the phre- noesophageal membrane. This results in a protrusion of a hernia sac containing intra-abdominal organs through the diaphragmatic hiatus and into the mediastinum. The preva- lence of large hiatal hernias increases with age, suggesting that environmental and tissue-aging factors are involved in the pathophysiology. In addition, there is a positive asso- ciation between the presence of hiatal and inguinal hernias, suggesting either a genetic predisposition affecting tissue integrity or some other common factor, such as increased intra-abdominal pressure.
UR - http://www.scopus.com/inward/record.url?scp=85053093113&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85053093113&partnerID=8YFLogxK
U2 - 10.1201/9781315113777
DO - 10.1201/9781315113777
M3 - Chapter
SN - 9781482299571
SP - 411
EP - 418
BT - Operative Thoracic Surgery, Sixth Edition
PB - CRC Press
ER -