Large artery disease in scleroderma: Case report and review of the literature

A. C. Rat, J. Varga*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Involvement of the large arteries in patients with systemic sclerosis (SSc) has been only rarely reported. We describe the case of a 56-year-old woman with early diffuse cutaneous SSc who presented with acute unilateral digital ischemia. Evaluation identified thrombosis at the site of a previous subclavian-to-common carotid artery bypass, rather than Raynaud's phenomenon, as the cause of ischemia. A review of the literature indicates that large artery involvement, although a relatively uncommon clinical manifestation, can be frequently detected in the lower limbs as well as the ulnar arteries in patients with SSc.

Original languageEnglish (US)
Pages (from-to)198-203
Number of pages6
JournalJournal of Clinical Rheumatology
Issue number4
StatePublished - Jan 1 2000


  • Arterial occlusive disease
  • Peripheral vascular disease
  • Raynaud's phenomenon
  • Scleroderma

ASJC Scopus subject areas

  • Rheumatology

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