Large-pore apertures in a series of metal-organic frameworks

Hexiang Deng, Sergio Grunder, Kyle E. Cordova, Cory Valente, Hiroyasu Furukawa, Mohamad Hmadeh, Felipe Gándara, Adam C. Whalley, Zheng Liu, Shunsuke Asahina, Hiroyoshi Kazumori, Michael O'Keeffe, Osamu Terasaki, J. Fraser Stoddart, Omar M. Yaghi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1663 Scopus citations


We report a strategy to expand the pore aperture of metal-organic frameworks (MOFs) into a previously unattained size regime (>32 angstroms). Specifically, the systematic expansion of a well-known MOF structure, MOF-74, from its original link of one phenylene ring (I) to two, three, four, five, six, seven, nine, and eleven (II to XI, respectively), afforded an isoreticular series of MOF-74 structures (termed IRMOF-74-I to XI) with pore apertures ranging from 14 to 98 angstroms. All members of this series have non-interpenetrating structures and exhibit robust architectures, as evidenced by their permanent porosity and high thermal stability (up to 300°C). The pore apertures of an oligoethylene glycol-functionalized IRMOF-74-VII and IRMOF-74-IX are large enough for natural proteins to enter the pores.

Original languageEnglish (US)
Pages (from-to)1018-1023
Number of pages6
Issue number6084
StatePublished - May 25 2012

ASJC Scopus subject areas

  • General


Dive into the research topics of 'Large-pore apertures in a series of metal-organic frameworks'. Together they form a unique fingerprint.

Cite this