Laser-scanning Doppler photoacoustic microscopy based on temporal correlation

Wei Song; Wenzhong Liu; Hao F. Zhang

doi:10.1063/1.4807290

Laser-scanning Doppler photoacoustic microscopy based on temporal correlation

Wei Song, Wenzhong Liu, Hao F. Zhang

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

We present a methodology to measure absolute flow velocity using laser-scanning photoacoustic microscopy. To obtain the Doppler angle, the angle between ultrasonic detection axis and flow direction, we extracted the distances between the transducer and three adjacent scanning points along the flow and repeatedly applied the law of cosines. To measure flow velocity along the ultrasonic detection axis, we calculated the time shift between two consecutive photoacoustic waves at the same scanning point, then converted the time shift to velocity according to the sound velocity and time interval between two laser illuminations. We verified our method by imaging flow phantoms.

Original language	English (US)
Article number	203501
Journal	Applied Physics Letters
Volume	102
Issue number	20
DOIs	https://doi.org/10.1063/1.4807290
State	Published - May 20 2013

ASJC Scopus subject areas

Physics and Astronomy (miscellaneous)

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10.1063/1.4807290

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title = "Laser-scanning Doppler photoacoustic microscopy based on temporal correlation",

abstract = "We present a methodology to measure absolute flow velocity using laser-scanning photoacoustic microscopy. To obtain the Doppler angle, the angle between ultrasonic detection axis and flow direction, we extracted the distances between the transducer and three adjacent scanning points along the flow and repeatedly applied the law of cosines. To measure flow velocity along the ultrasonic detection axis, we calculated the time shift between two consecutive photoacoustic waves at the same scanning point, then converted the time shift to velocity according to the sound velocity and time interval between two laser illuminations. We verified our method by imaging flow phantoms.",

author = "Wei Song and Wenzhong Liu and Zhang, {Hao F.}",

note = "Funding Information: We are grateful for the generous support from NSF Grant Nos. CBET-1055379 (CAREER) and CBET-1066776, and NIH Grant Nos. 1RC4EY021357, 1R01EY019951, and 1R24EY022883 to H.F.Z. We also thank the China Scholarship Council for supporting W.S.",

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N1 - Funding Information: We are grateful for the generous support from NSF Grant Nos. CBET-1055379 (CAREER) and CBET-1066776, and NIH Grant Nos. 1RC4EY021357, 1R01EY019951, and 1R24EY022883 to H.F.Z. We also thank the China Scholarship Council for supporting W.S.

PY - 2013/5/20

Y1 - 2013/5/20

N2 - We present a methodology to measure absolute flow velocity using laser-scanning photoacoustic microscopy. To obtain the Doppler angle, the angle between ultrasonic detection axis and flow direction, we extracted the distances between the transducer and three adjacent scanning points along the flow and repeatedly applied the law of cosines. To measure flow velocity along the ultrasonic detection axis, we calculated the time shift between two consecutive photoacoustic waves at the same scanning point, then converted the time shift to velocity according to the sound velocity and time interval between two laser illuminations. We verified our method by imaging flow phantoms.

AB - We present a methodology to measure absolute flow velocity using laser-scanning photoacoustic microscopy. To obtain the Doppler angle, the angle between ultrasonic detection axis and flow direction, we extracted the distances between the transducer and three adjacent scanning points along the flow and repeatedly applied the law of cosines. To measure flow velocity along the ultrasonic detection axis, we calculated the time shift between two consecutive photoacoustic waves at the same scanning point, then converted the time shift to velocity according to the sound velocity and time interval between two laser illuminations. We verified our method by imaging flow phantoms.

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Laser-scanning Doppler photoacoustic microscopy based on temporal correlation

Abstract

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