Laser-scanning optical-resolution photoacoustic microscopy

Zhixing Xie, Shuliang Jiao, Hao F. Zhang, Carmen A. Puliafito

Research output: Contribution to journalArticlepeer-review

180 Scopus citations


We have developed a laser-scanning optical-resolution photoacoustic microscopy method that can potentially fuse with existing optical microscopic imaging modalities. To acquire an image, the ultrasonic transducer is kept stationary during data acquisition, and only the laser light is raster scanned by an x-y galvanometer scanner. A lateral resolution of 7.8 μm and a circular field of view with a diameter of 6mm were achieved in an optically clear medium. Using a laser system working at a pulse repetition rate of 1024 Hz, the data acquisition time for an image consisting of 256×256 pixels was less than 2 min.

Original languageEnglish (US)
Pages (from-to)1771-1773
Number of pages3
JournalOptics Letters
Issue number12
StatePublished - Jun 15 2009

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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