Late recurrence of minimal lesion nephrotic syndrome

C. Pru, C. M. Kjellstrand, R. A. Cohn, R. L. Vernier

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Nephrotic syndrome recurred in 16 patients who had been free of the disease of an interval of 4 to 25 years. Their initial illness began in childhood and responsed to adrenocorticosteroid therapy; in 10 patients it was associated with few changes on light microscopic examination of kidney biopsy specimens. The late recurrence also responded to steroids, and in only 1 patient did low grade proteinuria persist after treatment. Renal biopsy specimens taken from 8 patients during late recurrence showed minimal-change nephrotic syndrome in 7 and focal segmental glomerulosclerosis in 1. Renal function remained normal in all patients. The late recurrence of minimal-change nephrotic syndrome has most of the features of that syndrome seen in the more typical childhood age group and should be managed similarly.

Original languageEnglish (US)
Pages (from-to)69-72
Number of pages4
JournalAnnals of internal medicine
Issue number1
StatePublished - 1984

ASJC Scopus subject areas

  • Internal Medicine


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