TY - JOUR
T1 - Learning to Encode Timing
T2 - Mechanisms of Plasticity in the Auditory Brainstem
AU - Tzounopoulos, Thanos
AU - Kraus, Nina
N1 - Funding Information:
We thank Dr. Donata Oertel, Dr. Karl Kandler, Dr. Bharath Chandrasekaran, Trent Nicol, and Maria A. Tsiarli for many helpful discussions and for critical reading of the manuscript. We also thank Dylan Lukes and Erika Skoe for help in making the figures. This work was supported by NIH/NIDCD grants R01 (DC007905 to T.T. and DC001510 to N.K.), by a grant from the American Tinnitus Association to T.T., and by an NSF grant (0544846 to N.K.).
PY - 2009/5/28
Y1 - 2009/5/28
N2 - Mechanisms of plasticity have traditionally been ascribed to higher-order sensory processing areas such as the cortex, whereas early sensory processing centers have been considered largely hard-wired. In agreement with this view, the auditory brainstem has been viewed as a nonplastic site, important for preserving temporal information and minimizing transmission delays. However, recent groundbreaking results from animal models and human studies have revealed remarkable evidence for cellular and behavioral mechanisms for learning and memory in the auditory brainstem.
AB - Mechanisms of plasticity have traditionally been ascribed to higher-order sensory processing areas such as the cortex, whereas early sensory processing centers have been considered largely hard-wired. In agreement with this view, the auditory brainstem has been viewed as a nonplastic site, important for preserving temporal information and minimizing transmission delays. However, recent groundbreaking results from animal models and human studies have revealed remarkable evidence for cellular and behavioral mechanisms for learning and memory in the auditory brainstem.
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U2 - 10.1016/j.neuron.2009.05.002
DO - 10.1016/j.neuron.2009.05.002
M3 - Short survey
C2 - 19477149
AN - SCOPUS:65649098685
SN - 0896-6273
VL - 62
SP - 463
EP - 469
JO - Neuron
JF - Neuron
IS - 4
ER -