Left Atrial Appendage Closure

Albert C. Lin; Bradley P. Knight

doi:10.1016/j.pcad.2015.07.009

Left Atrial Appendage Closure

Albert C. Lin^*, Bradley P. Knight

^*Corresponding author for this work

Medicine, Cardiology Division

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Stroke or systemic embolism is a devastating consequence of atrial fibrillation (AF) due to thrombus formation in the left atrial appendage (LAA). AF causes thrombus formation in the LAA due to both the loss of atrial systole and the unique anatomic features of the LAA. Oral anticoagulation is a well established and effective therapy to reduce the risk of stroke in AF patients, albeit with a risk of bleeding. LAA closure is a possible alternative to oral anticoagulation in the prevention of stroke or systemic embolism in AF.

Original language	English (US)
Pages (from-to)	195-201
Number of pages	7
Journal	Progress in Cardiovascular Diseases
Volume	58
Issue number	2
DOIs	https://doi.org/10.1016/j.pcad.2015.07.009
State	Published - Sep 1 2015

Keywords

Atrial fibrillation
Left atrial appendage
Left atrial appendage closure

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.pcad.2015.07.009

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title = "Left Atrial Appendage Closure",

abstract = "Stroke or systemic embolism is a devastating consequence of atrial fibrillation (AF) due to thrombus formation in the left atrial appendage (LAA). AF causes thrombus formation in the LAA due to both the loss of atrial systole and the unique anatomic features of the LAA. Oral anticoagulation is a well established and effective therapy to reduce the risk of stroke in AF patients, albeit with a risk of bleeding. LAA closure is a possible alternative to oral anticoagulation in the prevention of stroke or systemic embolism in AF.",

keywords = "Atrial fibrillation, Left atrial appendage, Left atrial appendage closure",

author = "Lin, {Albert C.} and Knight, {Bradley P.}",

note = "Funding Information: Albert Lin, MD: consultant, SentreHeart. Bradley Knight: consultant, speaking honoraria, and fellowship support: Boston Scientific; consultant, SentreHeart. Publisher Copyright: {\textcopyright} 2015.",

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AU - Lin, Albert C.

AU - Knight, Bradley P.

N1 - Funding Information: Albert Lin, MD: consultant, SentreHeart. Bradley Knight: consultant, speaking honoraria, and fellowship support: Boston Scientific; consultant, SentreHeart. Publisher Copyright: © 2015.

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Stroke or systemic embolism is a devastating consequence of atrial fibrillation (AF) due to thrombus formation in the left atrial appendage (LAA). AF causes thrombus formation in the LAA due to both the loss of atrial systole and the unique anatomic features of the LAA. Oral anticoagulation is a well established and effective therapy to reduce the risk of stroke in AF patients, albeit with a risk of bleeding. LAA closure is a possible alternative to oral anticoagulation in the prevention of stroke or systemic embolism in AF.

AB - Stroke or systemic embolism is a devastating consequence of atrial fibrillation (AF) due to thrombus formation in the left atrial appendage (LAA). AF causes thrombus formation in the LAA due to both the loss of atrial systole and the unique anatomic features of the LAA. Oral anticoagulation is a well established and effective therapy to reduce the risk of stroke in AF patients, albeit with a risk of bleeding. LAA closure is a possible alternative to oral anticoagulation in the prevention of stroke or systemic embolism in AF.

KW - Atrial fibrillation

KW - Left atrial appendage

KW - Left atrial appendage closure

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Left Atrial Appendage Closure

Abstract

Keywords

ASJC Scopus subject areas

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