Left-sided facial mass

Laura Swibel Rosenthal, Steven Garzon, Suman Setty, Mike Yao*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Spindle cell lipoma (SCL) is a rare variant of lipoma that has the gross appearance of a lipoma with white or gray gelatinous areas. Only 3 cases have been reported in the parotid area. Most cases are seen in the upper back and neck. Histologically, SCL features a uniform proliferation of spindle cells with single elongated nuclei in a matrix of collagen and mucoid material without "signet-ring" lipoblasts. Immunohistochemically, SCL shows diffuse cytoplasmic positivity for CD34 in the spindle cells. Spindle cell lipoma has histologic similarities to liposarcoma but is distinguished from it by a lack of cellular atypia and an absence of lipoblasts. In addition, liposarcoma is usually deep seated and less circumscribed compared to the superficial, well-circumscribed, and lobulated SCL.

Original languageEnglish (US)
Pages (from-to)875-876
Number of pages2
JournalArchives of Pathology and Laboratory Medicine
Issue number6
StatePublished - Jun 2006

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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