TY - CHAP
T1 - Left Ventricular Assist Device Infection
AU - Madamanchi, Chaitanya
AU - El-Dalati, Sami
AU - Tam, Marty
AU - Murthy, Venkatesh L.
AU - Weinberg, Richard L.
N1 - Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Left ventricular assist devices (LVADs) improve survival and quality of life for end-stage heart failure patients [1]. Unfortunately, infection is a critical and common complication in patients with LVADs [2]. Diagnosis of LVAD infection in a timely fashion enables the selection and prompt initiation of therapy. However, because of the multiple internal and external components of LVADs, diagnosis and characterization of the extent of infection is particularly challenging. Furthermore, many patients may have other cardiac and extracardiac prosthetic devices. In addition to a comprehensive evaluation including history and physical, cultures, and biomarkers, imaging tests have an important role in the diagnosis of LVAD infections. In particular, FDG-PET/CT has emerged as a powerful imaging technique with high sensitivity and clinical value for diagnosing LVAD infections when added to a thorough clinical evaluation [3]. This chapter will review the epidemiology, and pathophysiology of LVAD infections, present diagnostic strategies, and offer a case-based discussion illustrating the utility of FDG-PET/CT in diagnosing LVAD infections.
AB - Left ventricular assist devices (LVADs) improve survival and quality of life for end-stage heart failure patients [1]. Unfortunately, infection is a critical and common complication in patients with LVADs [2]. Diagnosis of LVAD infection in a timely fashion enables the selection and prompt initiation of therapy. However, because of the multiple internal and external components of LVADs, diagnosis and characterization of the extent of infection is particularly challenging. Furthermore, many patients may have other cardiac and extracardiac prosthetic devices. In addition to a comprehensive evaluation including history and physical, cultures, and biomarkers, imaging tests have an important role in the diagnosis of LVAD infections. In particular, FDG-PET/CT has emerged as a powerful imaging technique with high sensitivity and clinical value for diagnosing LVAD infections when added to a thorough clinical evaluation [3]. This chapter will review the epidemiology, and pathophysiology of LVAD infections, present diagnostic strategies, and offer a case-based discussion illustrating the utility of FDG-PET/CT in diagnosing LVAD infections.
KW - FDG-PET/CT
KW - Heart failure
KW - Imaging
KW - Infection
KW - Inflammation
KW - LVAD
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U2 - 10.1007/978-3-031-09807-9_16
DO - 10.1007/978-3-031-09807-9_16
M3 - Chapter
AN - SCOPUS:85163524388
SN - 9783031098062
SP - 207
EP - 224
BT - FDG-PET/CT and PET/MR in Cardiovascular Diseases
PB - Springer International Publishing
ER -