Left ventricular function after successful percutaneous transluminal coronary angioplasty for postinfarction angina pectoris

Hani N. Sabbah, James F. Brymer, Mihai Gheorghiade, Paul D. Stein, Fareed Khaja*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The purpose of this study was to determine if coronary revascularization by balloon angioplasty (PTCA) in patients with postinfarction angina can elicit an improvement of global systolic left ventricular (LV) function. LV function was evaluated in 18 patients with postinfarction angina based on peak aortic blood acceleration measured noninvasively with a continuous wave Doppler velocimeter. Initial Doppler measurements were made 4 ± 1 days after infarction and just before PTCA and were repeated 24 to 48 hours after PTCA. Patients were divided into 2 groups. Group I (n = 10) had successful PTCA (reperfusion). Group II (n = 8) either had an unsuccessful PTCA or did not undergo PTCA or thrombolytic therapy (no reperfusion). In group I patients, peak acceleration increased from 16 ± 1 m/s/s just before PTCA to 24 ± 2 m/s/s 24 to 48 hours after successful PTCA (p < 0.001). In group II patients, peak acceleration was 17 ± 2 m/s/s just before PTCA and remained relatively unchanged (18 ± 2 m/s/s) 24 to 48 hours later. These data indicate that revascularization of coronary arteries in patients with postinfarction angina can elicit considerable improvement of global LV systolic function.

Original languageEnglish (US)
Pages (from-to)358-362
Number of pages5
JournalThe American journal of cardiology
Volume62
Issue number7
DOIs
StatePublished - Sep 1 1988

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Left ventricular function after successful percutaneous transluminal coronary angioplasty for postinfarction angina pectoris'. Together they form a unique fingerprint.

Cite this