Left ventricular systolic dysfunction diastolic filling characteristics and exercise cardiac reserve in mitral stenosis

Byung il William Choi*, Stephen L. Bacharach, Deborah J. Barbour, Martin B. Leon, Kevin E. McCarthy, Robert O. Bonow

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

In summary, our data indicate that a significant number of patients with severe MS have LV systolic dysfunction. This results, at least in part, from diastolic flow reduction caused by the tight mitral valve and possibly by the poorly compliant LV posterior wall, which reduces LV end-diastolic volume. Although ejection fraction increases with exercise, LV filling is further compromised by the shorter diastolic periods at higher heart rates, resulting in a severe reduction in LV end-diastolic and stroke volumes, and an attenuated increase or actual decrease in cardiac output.

Original languageEnglish (US)
Pages (from-to)526-529
Number of pages4
JournalThe American journal of cardiology
Volume75
Issue number7
DOIs
StatePublished - Mar 1 1995

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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