Leiomyomatosis peritonealis disseminata, endometriosis, and multicystic mesothelioma: An unusual association

George Zotalis*, Ritu Nayar, David G. Hicks

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


A 32-year-old, previously healthy woman with a diffuse, complex tumoral process is described. While she was being evaluated for primary infertility, a laparoscopic procedure revealed a disseminated peritoneal process associated with bilateral ovarian lesions. A clinical diagnosis of stage III ovarian cancer was made and total hysterectomy, bilateral salpingo- oophorectomy, and omentectomy were performed. Pathologic studies showed an admixture of leiomyomatosis peritonealis disseminata (LPD) endometriosis, and an extensive multicystic mesothelial proliferation. Although endometriosis is known to Occur in conjunction with either LPD or multicystic mesothelioma, to our knowledge this is the first report of all three lesions occurring simultaneously.

Original languageEnglish (US)
Pages (from-to)178-182
Number of pages5
JournalInternational Journal of Gynecological Pathology
Issue number2
StatePublished - Jan 1 1998


  • Endometriosis
  • Leiomyomatosis peritonealis disseminata
  • Multicystic mesothelioma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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