Leptomeningeal metastases from recurrent squamous cell cancer of the skin

Martin Begemann*, Marc K. Rosenblum, John Loh, Dennis Kraus, Jeffrey J. Raizer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


We report two patients with leptomeningeal metastases from squamous cell cancer of the skin. In one patient cauda equina metastases appeared 6 years after initial presentation; the tumor from radical neck dissection demonstrated perineural invasion suggesting a possible route for subarachnoid dissemination. The other patient presented 2 years after initial diagnosis with confusion and cranial nerve seven and twelve palsies. Both patients died from complications of leptomeningeal metastases.

Original languageEnglish (US)
Pages (from-to)295-298
Number of pages4
JournalJournal of Neuro-Oncology
Issue number3
StatePublished - Jul 2003


  • Leptomeningeal metastases
  • Neurological complications
  • Perineural invasion
  • Squamous cell cancer

ASJC Scopus subject areas

  • Oncology
  • Neurology
  • Clinical Neurology
  • Cancer Research


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